run2: project proj_d059de8f2ed4 created 2026-09-06T22:31:21Z (backend 5dfed6d6 deploying)
run2: PICO pico_5865b6db8b8b complete 2026-09-06T22:33:21Z; backend 5dfed6d6 deployed
run2: CSR picked by hand; upload clicked 2026-09-06T22:42:51Z
run2: CSR ast_e88a541a073f uploaded, Preparing at 2026-09-06T22:43:59Z
run2: deliverable create clicked 2026-09-06T22:45:33Z
run2: deliverable ast_9b1163ad87be created ~22:45:30Z (801 fields, 8 prefilled)
run2: CSR ready (indexed) by 22:46:53Z
run2: Autofill this document clicked 2026-09-06T22:47:18Z
run2: CSR asset created 22:43:02Z, uploadedAt 22:43:46Z, indexedAt 22:46:51Z (229 s from create, 185 s from upload end), 7245 chunks, job idx_8fc5ee8060fa45d38f159629
run2: fill 22:47:18Z -> preparedAt 22:53:42Z (384 s); 791/791; answered 435, no-evidence 356
22:58:32 Sponsor name (538565650): Use suggestion -> "Novo Nordisk" in Table 1 (Filled 9/801).
23:00:10 Dosing and administration (230650760): Use suggestion -> 593-char answer, one passage p.40 (Filled 10/801).
23:00:52-23:01:02 Summarize field -> draft ("In the NN9536-4373 (STEP 1) trial, both semaglutide and placebo were investigational medicinal products ...") "All checks passed"; Replace field text.
23:01:08 local dev web server hot-reload -> every Palmera tab reloaded; API requests 10-20 s each for ~1 min while all tabs reloaded; document had been saved (PutFile 23:00:56, summarize accept 23:01:02).
23:05 Export DOCX exp_d939b1bb78e2441ab214457dea288f42 -> palmera/run2-export-after-accept-summarize.docx (930,089 bytes). export-diff vs template-c95-beta.docx: 802 controls both, changed 2 (538565650 Sponsor name; 230650760 dosing = summary prose), only-new 0, only-old 0. Provenance sidecar item5.xml: 2 accepted.
23:07 renders/run2-after.pdf, run2-after-p7-07.png (page 7 shows Sponsor "Novo Nordisk" and the dosing summary).
palmera-check-run2: 791 suggestions, answered 435, no-evidence 356 (352 related_passages_not_grounded, 4 none); passages 763: exact 632, words-on-page 120, partial 5 (appendix listing pages 666/677/679), not_found 1 (p.688 patient listing), too_short 5; page claims 752: correct 749, elsewhere 3; numbers 3781/3781 found in CSR.
2026-09-07T06:03:54Z Recommended dosage (1517267069): Use suggestion -> trial escalation regimen, passages p.39 and p.41 (Filled 11/801).
2026-09-07T06:05:10Z Mechanism of action (631054096): Use suggestion -> one passage p.32 §7.1 Background (Filled 12/801).
2026-09-07T06:05 Export DOCX -> palmera/palmera-export.docx (935,481 bytes). export-diff vs template: 4 controls changed (538565650, 230650760, 1517267069, 631054096); 50 pages.
2026-09-07T06:10-06:19 Mechanism of action tidied by hand in Word: the CSR's reference superscripts ("68-73", "74", "73, 75, 76") removed; two paragraphs joined. First attempt pressed Enter inside the field and split it into two (802 fields); joined again with Backspace (801).
2026-09-07T06:20 Export DOCX -> palmera/palmera-export.docx (935,458 bytes). export-diff vs template: 801 controls, 4 changed (538565650, 230650760, 1517267069, 631054096); 50 pages. Provenance record unchanged: 4 fieldReview entries.
2026-09-07T06:27 Recommended dosage: Summarize field -> prose draft with five soft warnings (number 9.3 not carried; protected phrase "placebo" not verbatim; frozen wording "9.3" absent; two near-verbatim stretches of 12 and 10 words). Read, then Replace field text.
2026-09-07T06:28 Export DOCX -> palmera/palmera-export.docx (935,301 bytes). export-diff vs template: 801 controls, 4 changed; 50 pages; provenance record: 4 fieldReview entries.
2026-09-07T07:53-08:06 Comment moved: the medical comment now sits on Recommended dosage (the field 9a, 5b and 9e show); the one on Dosing and administration removed. Along the way a stray keystroke overwrote Recommended dosage and Health Canada indication; both restored by hand to the exact previous text and checked against the template (Health Canada indication = agency text, unchanged).
2026-09-07T08:07 Export DOCX -> palmera/palmera-export.docx. export-diff vs template: 801 controls, 4 changed (Sponsor, Mechanism of action, Recommended dosage, Dosing and administration); comments.xml: 1 comment, anchored on Recommended dosage; provenance record: 4 fieldReview entries; 51 pages.
2026-09-07T08:12-08:20 The 08:07 export had a page break before Table 1 (a Ctrl+Return that landed in the document while the comment was being moved), so the table sat on page 8 and page 7 was empty. Removed in Word (Table Properties, Text Flow, Break off). Restoring Recommended dosage by hand had also removed the comment anchored in it, so the medical comment was posted again on that field. Writer's autocorrect left two curly apostrophes and a space after "discretion." in Recommended dosage; the words are unchanged.
2026-09-07T08:22 Export DOCX -> palmera/palmera-export.docx (935,317 bytes). export-diff vs template: 801 controls, 4 changed (Sponsor, Mechanism of action, Recommended dosage, Dosing and administration); no page break before Table 1; comments.xml: 1 comment, anchored on Recommended dosage; provenance record: 4 fieldReview entries; 50 pages. palmera-export-printed.pdf is this file rendered.
2026-09-07T08:28-08:36 The two autocorrected apostrophes and the space after "discretion." put back with Find and Replace in Word ("investigator’s" -> "investigator's", replaced 2 times; "discretion. If" -> "discretion.If", 1 time). Recommended dosage is now character for character the Summarize text of 06:27.
2026-09-07T08:36 Export DOCX -> palmera/palmera-export.docx (935,321 bytes). export-diff vs template: 801 controls, 4 changed (Sponsor, Mechanism of action, Recommended dosage, Dosing and administration); every field text identical to the 06:28 export; comments.xml: 1 comment, anchored on Recommended dosage; provenance record: 4 fieldReview entries; no page break before Table 1; 50 pages. palmera-export-printed.pdf is this file rendered.
2026-09-07T08:40-08:52 Two more corrections in Word. The Summarize text had a line break after "discretion." (not a space); put back with Shift+Enter at that position. Health Canada indication had lost Word's placeholder marker when it was retyped by hand; set again with "Current content is a prompt" on the template surface of the same document. A wrong click on the way put "discretion.If" into NOC date and a line break into the "Description" header; both undone in Word and checked.
2026-09-07T08:52 Export DOCX -> palmera/palmera-export.docx (935,334 bytes). Against the 06:28 export (the one made right after Summarize was applied): all 801 controls identical in text, line breaks, paragraphs, placeholder markers and control properties; provenance record identical; document text identical throughout; all 50 pages render pixel for pixel the same. Differences left in the XML: the comment on Recommended dosage, an explicit zero paragraph spacing on the "Item" header (written when the table dialog was confirmed), and run boundaries in two fields. palmera-export-printed.pdf is this file rendered.